Where are Peyer's patches primarily found?

Peyer's patches are specialized lymphoid tissues primarily located in the lining of the small intestine, specifically in the ileum. These structures play a crucial role in the immune response to intestinal pathogens and are vital for monitoring intestinal bacteria populations. Their presence in the intestinal lining allows for the sampling of antigens from the gut lumen, facilitating an immune response as necessary. This unique positioning in the diffusion within the intestines is key for their function, making the confirmation of their location essential for understanding intestinal immunity and the overall gut-associated lymphoid tissue (GALT) system.